Selected Publications

  1. Wei Tan*, Weizhou Zhang*, Amy Strasner, Sergei Grivennikov, Robert M. Hoffman, Jin Q. Cheng, Michael Karin. Tumor infiltrating CD4+ T cells stimulate mammary/breast cancer metastasis through activation of RANKL-RANK signaling. Nature. 2011, Feb 24;470(7335):548-53. (*equal contribution) PMID: 21326202; PMCID: PMC3166217.
  2. Weizhou Zhang, Wei Tan, Xuefeng Wu, Maxim Poustovoitov, Amy Strasner, Wei Li, Nicholas Borcherding, Majid Ghassemian, and Michael Karin. A NIK-IKKα module expands ErbB2-induced tumor- initiating cells by stimulating nuclear export of p27/Kip1. Cancer Cell. 2013 May 13;23(5):647-59. PMID: 23602409. PMCID: PMC3981467.
  3. Qing Xie, Julia Klesney-Tait, Kathy Keck, Corey Parlet, Nicholas Borcherding, Ryan Kolb, Wei Li, Lorraine Tygrett, Thomas Waldschmidt, Alicia Olivier, Songhai Chen, Guang-hui Liu, Xiangri Li, Weizhou Zhang*. Characterization of a novel mouse model with genetic deletion of CD177. Protein Cell. 2015 Feb;6(2):117-26. PMCID: PMC4312768. (*Corresponding author).
  4. Nicholas Borcherding, David Kusner, Ryan Kolb, Qing Xie, Wei Li, Gabriel Velez, Ryan Askeland, Ronald J. Weigel, Weizhou Zhang*. Paracrine Wnt5a signaling inhibits the expansion of tumor-initiating cells. Cancer Res. 2015 May 15;75(10):1972-82. PMID: 25769722; PMCID: PMC4433621. (*Corresponding author).
  5. Ryan Kolb, Fayyaz Sutterwala, Weizhou Zhang. Obesity and cancer: inflammation bridges the two. Current Opinion in Pharmacology. 2016 Aug;29:77-89. doi: 10.1016/j.coph.2016.07.005. PMID: 27429211. PMCID: PMC4992602.
  6. Fang Yuan, Ryan Kolb, Wei Li, Lin Sun, Fuyou Liu, Fayyaz S. Sutterwala, Yinghong Liu, Weizhou Zhang. Involvement of NLRC4-inflammasome in diabetic nephropathy. PLoS One. 2016 Oct 5;11(10):e0164135. PMID: 27706238. PMCID: PMC5051905.
  7. Ryan Kolb, Liem Phan, Nicholas Borcherding, Yinghong Liu, Fang Yuan, Ann M Janowski, Qing Xie, Kathleen R Markan, Wei Li, Matthew J Potthoff, Enrique Fuentes-Mattei, Lesley G Ellies, Michael Knudsen, Mong-Hong Lee, Sai-Ching Jim Yeung, Cassel L Suzanne, Fayyaz S Sutterwala, Weizhou Zhang*. Obesity-associated NLRC4 inflammasome promotes angiogenesis in breast cancer. Nature Communications. 2016. Oct 6;7:13007. Doi: 10.1038/ncomms13007. PMID: 27708283. (*Corresponding author).
  8. PTEN deficiency reporgrammes human neutral stem cells towards a glioblastoma stem cell-like phenotype. Shunlei Duan, Guohong Yuan, Xiaomeng Liu, Ruotong Ren, Jingyi Li, Weizhou Zhang, Jun Wu, Xiuling Xu, Lina Fu, Ying Li, Jiping Yang, Weiqi Zhang, Ruijun Bai, Fei Yi, Keiichiro Suzuki, Hua Gao, Concepcion Rodriguez Esteban, Chuanbao Zhang, Juan Carlos Izpisua Belmonte, Zhiguo Chen, Xiaoming Wang, Tao Jiang, Jing Qu, Fuchou Tang, Guang-Hui Liu. 2015. Nat Commun. 2015 Dec 3; 6:10068. PMID: 26632666; PMCID: PMC4686761.
  9. Huize Pan, Di Guan, Xiaomeng Liu, Jingyi Li, Lixia Wang, Jun Wu, Junzhi Zhou, Weizhou Zhang, Ruotong Ren, Weiqi Zhang, Ying Li, Jiping Yang, Ying Hao, Tingting Yuan, Guohong Yuan, Zhenyu Ju, Zhiyong Mao, Jian Li, Jing Qu, Fuchou Tang, Guang-Hui Liu. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by transactivating NRF2. Cell Res. 2016 Feb;26(2):190-205. PMID: 26768768; PMCID: PMC4746611.
  10. Ann M. Janowski, Oscar R. Colegio, Emma E. Hornick, Jennifer M. McNiff, Matthew D. Martin, Vladimir P. Badovinac, Lyse A. Norian, Weizhou Zhang, Suzanne L. Cassel, and Fayyaz S. Sutterwala. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016 Oct 3;126(10):3917-3928. PMID: 27617861. PMCID: PMC5096827.
  11. Ruotong Ren , Liping Deng , Yanhong Xue , Keiichiro Suzuki , Weiqi Zhang , Yang Yu , Jun Wu , Xiaoqing Ren , Si Wang , Weizhou Zhang, Fan Yang , Zhenyu Ju , Jian Li , Jie Qiao , Tao Xu , Jing qu, Guang-Hui Liu. Visualization of Aging-Associated Chromatin Alterations with an Engineered TALE System. Cell Research. 2017 Apr; 27(4):483-504. doi: 10.1038/cr.2017.18. PMID: 28139645; PMCID: PMC5385610.
  12. Peng Shao, Qi Liu, Peterson Kariuki Maina, Jiayue Cui, Thomas Bair, Tiandao Li, Shaikamjad Umesalma, Weizhou Zhang and Hank Heng Qi. Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis. Nucleic Acids Research. 2017 Feb 28;45(4):1687-1702. doi: 10.1093/nar/gkw1093. PMID: 27899639; PMCID: PMC5389682.

See complete list at [PubMed]